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Session includes invitee/speaker with CF. Others with CF encouraged to participate virtually.
Session includes invitee/speaker with CF. Others with CF encouraged to participate virtually.

IMI
Workshop

W12--Pathogenesis of CF Airway Infection

Thursday, September 26, 2024
10:15 AM - 12:15 PM ET
Location:206 AB

Recorded Session

This workshop highlights recent advances in the understanding of host-pathogen and pathogen-pathogen interactions in the development of CF airway infection. Abstracts selected for presentation address emerging concepts in infection pathogenesis, particularly how interactions among the host, bacteria, viruses, and fungi shape pathogen persistence and virulence in the lung.

Learning Objectives:

  • Define how host-pathogen interactions in the CF airway promote chronic Pseudomonas infection
  • Identify new mechanisms by which interkingdom interactions impair pathogen clearance in the lung
  • Recognize how antibiotic exposure and innate immune dysfunction each contribute to airway infection pathogenesis

Presentations:

  • 10:15 AM - 12:15 PM ET
    W12.1- Oxidative stress and metabolic dysregulation promote <em>P. aeruginosa </em>biofilms during coinfections in CF

    Speaker: Julianna Donohoe (she/her/hers) – Dartmouth College

  • 10:15 AM - 12:15 PM ET
    W12.2- The role of macrophage Piezo1 on bacterial clearance in Cystic Fibrosis

    Speaker: Erica M. Orsini, MD (she/her/hers) – Cleveland Clinic

  • 10:15 AM - 12:15 PM ET
    W12.3- Inactivating mutations in the MexEFoprN antibiotic efflux pump of Pseudomonas aeruginosa Cystic Fibrosis clinical isolates enhance virulence

    Speaker: Sheryl E. Fernandes, n/a (she/her/hers) – Cedars Sinai Medical Center

  • 10:15 AM - 12:15 PM ET
    W12.4- The epitranscriptomic regulation of Candida albicans infection in cystic fibrosis model.

    Presenting Author: Sohail Khoshnevis, PhD (he/him/his) – Emory University School of Medicine

  • 10:15 AM - 12:15 PM ET
    W12.5- Ketogenesis enables disease tolerance during P. aeruginosa pulmonary infection

    Speaker: Sebastian A. Riquelme, PhD – Columbia University