Yale University
Dr. Britto is a physician scientist investigating pulmonary innate immunity with a focus on CF and host-pathogen interactions in the airway epithelium. The overall goal of his research program is to define immune cell subset contributions to clinical variability and therapy response in subjects with CF or respiratory infections. His team is currently focused on: 1) Mechanistic studies on the role of airway host defense proteins in regulating lung inflammation during infection and 2) Human translational studies of airway inflammation with emphasis on transcriptomic profiling of airway immune cells and development of sputum biomarkers to predict exacerbations. In work with his collaborators, his laboratory performed the first mass-cytometry characterization of immune cells in sputum (2018), and more recently the first single-cell transcriptomic profiling of immune cells in the sputum of CF subjects (2020). This study represents a groundbreaking advance in the field of transcriptomics and airway inflammation in CF, and has garnered national and international recognition. Apart from his research, Dr. Britto cares for adult CF patients at the Yale Adult CF Program of the Yale University School of Medicine and contributes to healthcare education initiatives within the CFF's Genetic Therapies Working Group.
Junior Investigator Poster Judging Time
Thursday, September 26, 2024
12:30 PM – 2:00 PM ET
Junior Investigators Best Abstract in Basic Science
Friday, September 27, 2024
12:30 PM – 1:30 PM ET