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Viral Shah

MGH

Viral Shah, MD, PhD, Instructor in Medicine at Harvard Medical School and Massachusetts General Hospital.
Viral completed his MD/PhD training at the University of Iowa, under the mentorship of Dr. Michael Welsh. Viral's graduate work focused on understanding the mechanisms controlling airway surface liquid (ASL) pH and the role in CF. His primary work identified a new therapeutic target at treating CF by reducing acid secretion by blocking a proton pump in the lungs and was published in Science (PMC4852973). He then completed my clinical training at MGH (residency) and the Harvard Combined Pulmonary and Critical Care fellowship and begun a research program understanding the role of airway epithelial cells in health and disease. Specifically, he focuses on two newly discovered airway epithelial cells, the ionocyte and the hillock, under the guidance of Dr. Jay Rajagopal at MGH. He was awarded a CFF LeRoy Mathews grant for the project titled "Defining the Role of the Ionocyte in Cystic Fibrosis". He also recently described the novel role of the hillock in mouse and human airways, which was published in Nature (PMID: 38693267). In the future, Dr. Shah hopes to start his own lab focusing on the restoration of airway surface physiology after injury.

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