W01.1- Reduction in positive cultures for NTM and pulmonary disease in people with CF in the era of highly effective modulator therapy among participants in the longitudinal PREDICT study
W01.3- Integrative computational analysis of longitudinal effects of elexacaftor/tezacaftor/ivacaftor on sputum microbiome and proteome in patients with cystic fibrosis
TPS02.6- Lung-resident B- and T- cell responses limit AAV6.2 redelivery to the mouse lung
Location: Theater A (Exhibit & Poster Hall)
Speaker: Jay Kolls, MD – Tulane University School of Medicine
IMIAPPTT
Thursday, Sep 26th
12:30 PM – 2:00 PM ET
TPS02.7- Tolerization of lymphocytes and dysregulation of low-density neutrophils are key features of PBMCs from patients with cystic fibrosis, following live Pseudomonas aeruginosa infection.
TPS02.8- Single-cell RNA sequencing of circulating peripheral blood mononuclear cells from people with cystic fibrosis and nontuberculous mycobacteria pulmonary disease.
TPS02.9- Combined therapeutic strategies to favor the repair and regeneration of airway epithelium in cystic fibrosis despite the presence of bacterial infection
TPS02.10- Aspergillus fumigatus germination is mucus concentration dependent, affected by modulator changes to sputum, and promoted by Th2 cytokine stimulation in Cystic Fibrosis
RFPT05.3- Exploring multiple sampling techniques to characterise the airway microbiota in people with CF (pwCF) on ETI (elexacaftor/tezacaftor/ivacaftor) and a history of P. aeruginosa (PA) colonisation
RFPT05.5- Reliability of clinic-obtained versus self-obtained respiratory samples from the Self-Sample Accuracy and Benefit Implementation Trial (S2wAB-IT)
RFPT05.6- A Prospective Standardized Assessment of People with CF and Non-tuberculosis Mycobacteria Pulmonary Disease Undergoing Treatment with Bacteriophage: Design and Initial Results of the POSTSTAMP Study
Chair: Marcus A. Mall – Department of Pediatric Respiratory Medicine, Immunology and Intensive Care Medicine, Charité, Universitätsmedizin, Berlin, Germany
W20.3- Lactic acid producing bacteria are increased in CFTR-deficient colon crypt microbiota and lactate potentiates clonogenicity and stem cell capacity in colonic organoids and cancer cells.
W30.2- Chronic Staphylococcus aureus infection alters the lung metabolome to promote co-colonization with Pseudomonas aeruginosa in the cystic fibrosis rat.
W38.4- Safety and efficacy of nebulized phage in CF patients with chronic Pseudomonas aeruginosa pulmonary infection: A phase 1b/2a randomized, double-blind, placebo-controlled, multicenter study
